Scientific Knowledge on the Subject
Long-term exposure to ambient air pollution has been associated with reduced lung function in children. However, the role of timing of exposure remains unclear as well as possible effect modification by allergic status and other factors.
What This Study Adds to the Field
In this prospective birth cohort study we found association between traffic-related air pollution exposure during infancy and decreased lung function in children up to 8 years of age. Our results suggest stronger effects in children sensitized to common allergens. Early life exposure to traffic-related air pollution seems to have long-term respiratory consequences in susceptible groups such as atopic children.
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